Lipid panel · HDL cholesterol

What does HDL cholesterol mean on your blood test?

HDL is often called the “good” cholesterol because it helps carry other cholesterol out of your arteries and back to your liver. With HDL, a higher number is generally better. Here is how to read yours.

Higher is better
60 and above
mg/dL
At-risk (men)
Below 40
mg/dL
At-risk (women)
Below 50
mg/dL

What HDL is

High-density lipoprotein, or HDL, is one of the packages that carries cholesterol in your blood. HDL helps move cholesterol away from your arteries and back to your liver, where it can be removed. Because of that role, a higher HDL level is generally protective, which is the opposite of how LDL works.

How to read your HDL number

HDL is reported in mg/dL on your lipid panel. Unlike most lab values, here you generally want the number to be higher. A very low HDL can be a risk signal for heart disease. Your clinician reads HDL alongside your LDL, total cholesterol, and triglycerides rather than on its own.

What a low HDL can mean

A low HDL can be influenced by physical inactivity, smoking, excess weight, type 2 diabetes, and genetics. On its own it is not a diagnosis. It is one part of your heart-disease risk picture, and your clinician will weigh it against your other results and health history.

See your own HDL explained

Upload your lipid panel and Mednex explains HDL, LDL, and triglycerides together, then keeps the trend so you can see change over time.

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Common questions

Why do I want HDL to be high?
Because HDL helps carry cholesterol out of your arteries and back to the liver for removal. A higher HDL is generally associated with lower heart-disease risk, which is why the target direction is the opposite of LDL.
What is a good HDL level?
An HDL of 60 mg/dL or higher is generally viewed as protective. Levels below 40 mg/dL in men and below 50 mg/dL in women are often considered a risk factor. Your clinician interprets this together with the rest of your panel.
Can I raise my HDL?
Regular physical activity, not smoking, and reaching a healthy weight can help support HDL for many people. Any changes to treatment should be discussed with your clinician.

Sources

  1. MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); Cholesterol Levels; [cited 2026 Jul 9]. Available from: https://medlineplus.gov/lab-tests/cholesterol-levels/
  2. MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); HDL: The “Good” Cholesterol; [cited 2026 Jul 9]. Available from: https://medlineplus.gov/hdlthegoodcholesterol.html
  3. National Heart, Lung, and Blood Institute (US); Blood Cholesterol; [cited 2026 Jul 9]. Available from: https://www.nhlbi.nih.gov/health/blood-cholesterol

Content last reviewed 9 July 2026. Reference ranges vary by laboratory; always read your results against the range printed on your own report.

This page explains a common lab marker in general terms using public information from the U.S. National Library of Medicine and other NIH sources. It is educational and is not a diagnosis or medical advice. Reference ranges differ between laboratories and the meaning of a result depends on your age, sex, medications, and overall health. Always discuss your own results with the clinician who ordered them.