Inflammation marker - CRP

What does C-reactive protein (CRP) mean on your blood test?

C-reactive protein, or CRP, is made by your liver and rises when there is inflammation in your body. It is a sensitive signal, but it does not say where the inflammation is. Here is how to read it.

Reported as
CRP or high-sensitivity CRP
mg/L
A high CRP
Signals inflammation somewhere
non-specific

What CRP is

C-reactive protein is a substance your liver releases into the blood when there is inflammation in the body. Because it goes up in response to many kinds of inflammation, from infection to injury to chronic conditions, CRP is a sensitive but non-specific marker. It is measured in mg/L.

How to read your CRP

A higher CRP tells you that inflammation is likely present somewhere, but on its own it does not tell you the cause or the location. There is also a high-sensitivity version, hs-CRP, used in a different context related to heart-disease risk. Your clinician interprets which test you had and what the level means alongside your symptoms.

What a high level can mean

An elevated CRP can accompany infections, injuries, and inflammatory or autoimmune conditions, among many other causes. Because it is non-specific, it is most useful as one piece of information rather than a diagnosis. Your clinician uses it together with your history, examination, and other tests.

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Common questions

Does a high CRP mean I have an infection?
Not necessarily. CRP rises with many kinds of inflammation, including infections, injuries, and inflammatory conditions. Because it is non-specific, a high CRP signals inflammation somewhere but does not identify the cause on its own.
What is the difference between CRP and hs-CRP?
hs-CRP is a high-sensitivity version of the test able to detect lower levels, and it is used in a different context related to heart-disease risk assessment. Standard CRP is more often used to look at general inflammation. Your clinician chooses which fits your situation.
Can CRP be normal even if something is wrong?
Yes. CRP is one marker among many and does not capture every problem. It is interpreted alongside your symptoms, examination, and other tests rather than used alone.

Sources

  1. MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); C-Reactive Protein (CRP) Test; [cited 2026 Jul 9]. Available from: https://medlineplus.gov/lab-tests/c-reactive-protein-crp-test/
  2. MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); Heart Diseases; [cited 2026 Jul 9]. Available from: https://medlineplus.gov/heartdiseases.html
  3. MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); Autoimmune Diseases; [cited 2026 Jul 9]. Available from: https://medlineplus.gov/autoimmunediseases.html

Content last reviewed 9 July 2026. Reference ranges vary by laboratory; always read your results against the range printed on your own report.

This page explains a common lab marker in general terms using public information from the U.S. National Library of Medicine and other NIH sources. It is educational and is not a diagnosis or medical advice. Reference ranges differ between laboratories and the meaning of a result depends on your age, sex, medications, and overall health. Always discuss your own results with the clinician who ordered them.